منابع مشابه
Proteomics in Diagnostics
Over the history of medicine, man has developed effective ways to treat many diseases that he has been presented with. The treatments range from prevention in the form of vaccination to the use of medicines and surgical intervention as cures or even treatments to control the diseases effect on the patients’ quality of life. For many diseases, such as heart disease and cancer, early detection pl...
متن کاملSalivary diagnostics powered by nanotechnologies, proteomics and genomics.
BACKGROUND The ability to monitor health status, disease onset and progression, and treatment outcome through noninvasive means is a highly desirable goal in health care promotion and delivery. Oral fluid is a perfect medium to be explored for health and disease surveillance. METHODS Two prerequisites exist before the goal of salivary diagnostics can be achieved: identification of specific bi...
متن کاملA Novel Proteomics-Based Clinical Diagnostics Technology Identifies Heterogeneity in Activated Signaling Pathways in Gastric Cancers
PURPOSE The aim of this study was to utilize the proteomics-based Collaborative Enzyme Enhanced Reactive (CEER) immunoassay to investigate protein tyrosine phosphorylations as diagnostic markers in gastric cancers (GCs). EXPERIMENTAL DESIGN Protein lysates from fresh-frozen 434 advanced stage GCs were analyzed for phosphorylation of HER1, HER2, p95HER2, HER3, cMET, IGF1R and PI3K. The pathway...
متن کاملCurrent Trends in Microfluidics for Single Cell Isolation in Cancer Diagnostics Enabling Downstream Proteomics Applications
Cancer Diagnosis technologies are changing the healthcare scenario worldwide with huge socioeconomic impact. As we move into an era of individual personalized treatment the need for more sophisticated cancer diagnostics has emerged [1,2]. To date, cancer diagnosis and metastasis monitoring is mainly carried out through tissue biopsy and/or re-biopsy, a very invasive procedure limited only to ce...
متن کاملPharmaceutical Advances and Proteomics Researches
Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...
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ژورنال
عنوان ژورنال: Disease Markers
سال: 2004
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2004/509356